Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock
Sepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for th...
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Veröffentlicht in: | Journal of critical care 2019-12, Vol.54, p.228-234 |
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creator | Nabzdyk, Christoph S. Couture, Etienne J. Shelton, Kenneth Cudemus, Gaston Bittner, Edward A. |
description | Sepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example.
•Sepsis can induce stress cardiomyopathy (takotsubo) and sepsis-induced cardiomyopathy resulting in cardiogenic shock•The article reviews these two acute cardiomyopathies and the role of mechanical circulatory support in these patients.•An algorithm to the care of patients with septic shock and worsening end-organ perfusion is provided. |
doi_str_mv | 10.1016/j.jcrc.2019.09.001 |
format | Article |
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•Sepsis can induce stress cardiomyopathy (takotsubo) and sepsis-induced cardiomyopathy resulting in cardiogenic shock•The article reviews these two acute cardiomyopathies and the role of mechanical circulatory support in these patients.•An algorithm to the care of patients with septic shock and worsening end-organ perfusion is provided.</description><identifier>ISSN: 0883-9441</identifier><identifier>EISSN: 1557-8615</identifier><identifier>DOI: 10.1016/j.jcrc.2019.09.001</identifier><identifier>PMID: 31630071</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Blood ; Cardiomyopathy ; Catheters ; Critical care ; Extracorporeal membrane oxygenation ; Family medical history ; Heart ; Hospitals ; Literature reviews ; Morbidity ; Mortality ; Multiple organ dysfunction syndrome ; Patients ; Pulmonary arteries ; Sepsis</subject><ispartof>Journal of critical care, 2019-12, Vol.54, p.228-234</ispartof><rights>2019</rights><rights>Copyright © 2019. Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Dec 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-88c1bf2a50a8010eb65a302db0bcc0629515fc4b9607cc7f23d938eb88184cd13</citedby><cites>FETCH-LOGICAL-c384t-88c1bf2a50a8010eb65a302db0bcc0629515fc4b9607cc7f23d938eb88184cd13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0883944119306173$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31630071$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nabzdyk, Christoph S.</creatorcontrib><creatorcontrib>Couture, Etienne J.</creatorcontrib><creatorcontrib>Shelton, Kenneth</creatorcontrib><creatorcontrib>Cudemus, Gaston</creatorcontrib><creatorcontrib>Bittner, Edward A.</creatorcontrib><title>Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock</title><title>Journal of critical care</title><addtitle>J Crit Care</addtitle><description>Sepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example.
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In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example.
•Sepsis can induce stress cardiomyopathy (takotsubo) and sepsis-induced cardiomyopathy resulting in cardiogenic shock•The article reviews these two acute cardiomyopathies and the role of mechanical circulatory support in these patients.•An algorithm to the care of patients with septic shock and worsening end-organ perfusion is provided.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>31630071</pmid><doi>10.1016/j.jcrc.2019.09.001</doi><tpages>7</tpages></addata></record> |
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subjects | Blood Cardiomyopathy Catheters Critical care Extracorporeal membrane oxygenation Family medical history Heart Hospitals Literature reviews Morbidity Mortality Multiple organ dysfunction syndrome Patients Pulmonary arteries Sepsis |
title | Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock |
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