Development and validation of a new prediction model for graft function using preoperative marginal factors in living-donor kidney transplantation

Background Recently, living-donor kidney transplantation from marginal donors has been increasing. However, a simple prediction model for graft function including preoperative marginal factors is limited. Here, we developed and validated a new prediction model for graft function using preoperative m...

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Veröffentlicht in:	Clinical and experimental nephrology 2019-11, Vol.23 (11), p.1331-1340
Hauptverfasser:	Matsukuma, Yuta, Masutani, Kosuke, Tanaka, Shigeru, Tsuchimoto, Akihiro, Nakano, Toshiaki, Okabe, Yasuhiro, Kakuta, Yoichi, Okumi, Masayoshi, Tsuruya, Kazuhiko, Nakamura, Masafumi, Kitazono, Takanari, Tanabe, Kazunari
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Allografts - pathology Allografts - physiopathology Arteriosclerosis Atherosclerosis - pathology Atherosclerosis - physiopathology Biopsy Body Weight Donors Female Forecasting - methods Glomerular Filtration Rate Glomerulosclerosis, Focal Segmental - pathology Glomerulosclerosis, Focal Segmental - physiopathology Humans Hypertension Hypertension - physiopathology Kidney Transplantation Kidney transplants Living Donors Male Medicine Medicine & Public Health Middle Aged Models, Statistical Nephrology Original Article Patients Prediction models Preoperative Period Retrospective Studies Urology
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Zusammenfassung:	Background Recently, living-donor kidney transplantation from marginal donors has been increasing. However, a simple prediction model for graft function including preoperative marginal factors is limited. Here, we developed and validated a new prediction model for graft function using preoperative marginal factors in living-donor kidney transplantation. Methods We retrospectively investigated 343 patients who underwent living-donor kidney transplantation at Kyushu University Hospital (derivation cohort). Low graft function was defined as an estimated glomerular filtration rate of
ISSN:	1342-1751 1437-7799
DOI:	10.1007/s10157-019-01774-x