Sural nerve sensory response in diabetic distal symmetrical polyneuropathy

Sural nerve sensory response in diabetic distal symmetrical polyneuropathy

Introduction The sural sensory nerve action potential (SNAP) amplitude is a measure of the number of axons. We tested the hypothesis that sural SNAP amplitude can be used as a marker in screening, severity evaluation, and follow‐up of diabetic distal symmetrical polyneuropathy (DSPN). Methods Patien...

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Veröffentlicht in:Muscle & nerve 2020-01, Vol.61 (1), p.88-94
Hauptverfasser: Lai, Yun‐Ru, Huang, Chih‐Cheng, Chiu, Wen‐Chan, Liu, Rue‐Tsuan, Tsai, Nai‐Wen, Wang, Hung‐Chen, Lin, Wei‐Che, Cheng, Ben‐Chung, Su, Yu‐Jih, Su, Chih‐Min, Hsiao, Sheng‐Yuan, Chang, Hsueh‐Wen, Chen, Jung‐Fu, Ko, Jih‐Yang, Lu, Cheng‐Hsien
Format: Artikel
Sprache:eng
Schlagworte:
Action potential
Action Potentials
Adult
Aged
Aged, 80 and over
Aging
Amplitudes
Axons
Axons - pathology
composite amplitudes score
Cross-Sectional Studies
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - pathology
diabetic distal symmetrical polyneuropathy
Diabetic Neuropathies - physiopathology
Disease Progression
Electrodiagnosis
Evaluation
Female
Follow-Up Studies
follow‐up
Humans
Male
Middle Aged
Nerve conduction
Neural Conduction
Polyneuropathy
Prospective Studies
Screening
Sensory neurons
Sensory Receptor Cells
severity evaluation
Sural nerve
Sural Nerve - physiopathology
sural sensory nerve action potential
type 2 diabetes
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Zusammenfassung:Introduction The sural sensory nerve action potential (SNAP) amplitude is a measure of the number of axons. We tested the hypothesis that sural SNAP amplitude can be used as a marker in screening, severity evaluation, and follow‐up of diabetic distal symmetrical polyneuropathy (DSPN). Methods Patients with type 2 diabetes underwent nerve conduction studies and were followed for 6 years. Composite amplitude scores (CASs) were determined to evaluate DSPN severity. Results Sural SNAP amplitudes were negatively correlated with CAS (r = −.790, P 
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.26739