Simple Renal Cysts Are Associated With 24-Month Prognosis of Patients With Type B Aortic Dissection and Hypertension
The association of simple renal cyst (SRC) with type B aortic dissection (BAD) has recently been established. However, no studies have examined adverse events after BAD hospitalization among patients with SRC. In this study, we assessed the prognostic value of SRC in BAD patients with hypertension a...
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Veröffentlicht in: | Canadian journal of cardiology 2019-11, Vol.35 (11), p.1499-1504 |
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Zusammenfassung: | The association of simple renal cyst (SRC) with type B aortic dissection (BAD) has recently been established. However, no studies have examined adverse events after BAD hospitalization among patients with SRC. In this study, we assessed the prognostic value of SRC in BAD patients with hypertension after thoracic endovascular aortic repair (TEVAR).
We studied all BAD patients with hypertension who were admitted for TEVAR (n = 238; age 56.1 ± 9.8 years, 84.0% male). Aortic-related adverse events (ARAE) were evaluated as outcomes at 3 months and 24 months after TEVAR.
Among the total number of patients, 104 (43.7%) had at least 1 SRC. Patients with SRC were significantly older than those without (59.6 ± 8.8 vs 53.3 ± 9.7; P < 0.001). Patients with SRC were also more likely to suffer from peripheral arterial disease (55.8% vs 40.3%; P = 0.018) and cerebrovascular accidents (47.1% vs 29.9%; P = 0.006) than those without. Median follow-up for the 238 patients was 18.5 (range 6.4-24.0) months. Cumulative ARAE-free rates were 94.5 ± 1.5% at the 3-month follow-up and 81.5 ± 2.8% at the 24-month follow-up. Independent predictors of 3-month ARAE were found to be insertion of ≥ 2 stents (hazard ratio [HR] 3.977, 95% confidence interval [CI] 1.224-12.920; P = 0.022). For 24-month follow-up, SRC (HR 1.962, 95% CI 1.023-3.764; P = 0.043) was evaluated as the only independent predictive factor. SRC (HR 8.841, 95% CI 1.726-45.294; P = 0.009) was also evaluated as an independent predictive factor for 24-month ARAEs in the chronic group, but not in the acute or the subacute group.
SRC could predict 24-month ARAE in BAD patients with hypertension after TEVAR, especially in the chronic group.
L’existence d’un lien entre la présence d’un kyste rénal simple (KRS) et celle d’une dissection aortique de type B (DAB) a récemment été établie. Toutefois, aucune étude ne s’était penchée sur les événements indésirables survenant après une hospitalisation visant à traiter une DAB chez les patients présentant un KRS. Nous avons évalué la valeur pronostique de la présence d’un KRS chez les patients présentant une DAB et de l’hypertension après une réparation endovasculaire de l’aorte thoracique (TEVAR).
Nous avons examiné les cas de tous les patients présentant une DAB et de l’hypertension qui ont été admis pour une TEVAR (n = 238; âge : 56,1 ± 9,8 ans, 84,0 % de sexe masculin). Les événements indésirables liés à l’aorte (EIA) ont été évalués 3 mois et 24 mois après la TEVAR.
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ISSN: | 0828-282X 1916-7075 |
DOI: | 10.1016/j.cjca.2019.07.631 |