Effects of dietary protein intake on renal outcome and mortality in patients with advanced diabetic nephropathy

Background The difficulty of adhering to a low-protein diet is a serious limitation of randomized controlled trials aimed at validating the efficacy of this therapy. In this observational study of patients with diabetic nephropathy, we examined the association of dietary protein intake (DPI) with re...

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Veröffentlicht in:Clinical and experimental nephrology 2020-02, Vol.24 (2), p.119-125
Hauptverfasser: Tauchi, Eriko, Hanai, Ko, Babazono, Tetsuya
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Sprache:eng
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Zusammenfassung:Background The difficulty of adhering to a low-protein diet is a serious limitation of randomized controlled trials aimed at validating the efficacy of this therapy. In this observational study of patients with diabetic nephropathy, we examined the association of dietary protein intake (DPI) with renal outcome and mortality, taking into account the nutritional status. Methods We conducted a single-center historical cohort study of 449 adult Japanese patients with type 2 diabetes and the urinary albumin-to-creatinine ratio of ≥ 300 mg/g or estimated glomerular filtration rate of 
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-019-01796-5