Optimization of intravoxel incoherent motion (IVIM): variability of parameters measurements using a reduced distribution of b values for breast tumors analysis

Objectives This study aimed to examine the variability of intravoxel incoherent motion measurements acquired from reduced distributions of b values for breast tumors analysis. Materials and methods The investigations were carried out on twenty-four patients with diagnosed breast tumors. A conventional unenhanced MRI and various IVIM series preset with different distributions of b values (0–1000 s/mm 2 ) were performed. We assessed the variability in D slow , D fast , and PF measurements for different distributions of 9 to 4 b values compared with the IVIM metrics for 10 b values using Wilcoxon-Signed rank test. The data was statistically significant at P