Intraoperative Events in Liver Transplantation Using Donation After Circulatory Death Donors

Liver grafts from donation after circulatory death (DCD) are a source of organs to decrease wait‐list mortality. While there have been lower rates of graft loss, there are concerns of an increased incidence of intraoperative events in recipients of DCD grafts. We aim to look at the incidence of intr...

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Veröffentlicht in:Liver transplantation 2019-12, Vol.25 (12), p.1833-1840
Hauptverfasser: Chadha, Ryan M., Croome, Kristopher P., Aniskevich, Stephen, Pai, Sher‐Lu, Nguyen, Justin, Burns, Justin, Perry, Dana, Taner, C. Burcin
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Sprache:eng
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Zusammenfassung:Liver grafts from donation after circulatory death (DCD) are a source of organs to decrease wait‐list mortality. While there have been lower rates of graft loss, there are concerns of an increased incidence of intraoperative events in recipients of DCD grafts. We aim to look at the incidence of intraoperative events between recipients of livers from DCD and donation after brain death (DBD) donors. We collected data for 235 DCD liver recipients between 2006 and 2017. We performed a 1:1 propensity match between these patients and patients with DBD donors. Variables included recipient age, liver disease etiology, biological Model for End‐Stage Liver Disease (MELD) score, allocation MELD score, diagnosis of hepatocellular carcinoma, and year of transplantation. DCD and DBD groups had no significant differences in incidence of postreperfusion syndrome (P = 0.75), arrhythmia requiring cardiopulmonary resuscitation (P = 0.66), and treatments for hyperkalemia (P = 0.84). In the DCD group, there was a significant increase in amount of total intraoperative and postreperfusion blood products (with exception of postreperfusion packed red blood cells) utilized (P 
ISSN:1527-6465
1527-6473
DOI:10.1002/lt.25643