Fabrication of a Tyrosine-Responsive Liquid Quantum Dots Based Biosensor through Host–Guest Chemistry
Design and fabrication of smart liquid quantum dots (LQDs) with high biomolecule selectivity and specificity remains a challenge. Herein, a multifunctional calix[4]arene derivative (PCAD) was rationally designed and applied to fabricate a Tyr-responsive CdSe-LQD system through host–guest chemistry....
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| Veröffentlicht in: | Analytical chemistry (Washington) 2019-10, Vol.91 (20), p.13285-13289 |
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| container_title | Analytical chemistry (Washington) |
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| creator | Lu, Xiaoju Zhan, Yibei Ouyang, Qingying Bai, Suya Chen, Huan Yu, Yongliang Zheng, Yifu Sun, Yao Li, Haibing |
| description | Design and fabrication of smart liquid quantum dots (LQDs) with high biomolecule selectivity and specificity remains a challenge. Herein, a multifunctional calix[4]arene derivative (PCAD) was rationally designed and applied to fabricate a Tyr-responsive CdSe-LQD system through host–guest chemistry. Such a biosensor displays an outstanding fluorescence/macroscopic response for Tyr and reversible fluidic features due to the hydrogen interaction between the PCAD of CdSe-LQDs and Tyr. These excellent results highlighted CdSe-LQDs as a promising platform for biological molecule recognition and separation in the future. |
| doi_str_mv | 10.1021/acs.analchem.9b04034 |
| format | Article |
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Herein, a multifunctional calix[4]arene derivative (PCAD) was rationally designed and applied to fabricate a Tyr-responsive CdSe-LQD system through host–guest chemistry. Such a biosensor displays an outstanding fluorescence/macroscopic response for Tyr and reversible fluidic features due to the hydrogen interaction between the PCAD of CdSe-LQDs and Tyr. 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| source | ACS Publications |
| subjects | Analytical chemistry Biomolecules Biosensors Chemistry Fabrication Fluorescence Organic chemistry Quantum dots Selectivity Supramolecular compounds Tyrosine |
| title | Fabrication of a Tyrosine-Responsive Liquid Quantum Dots Based Biosensor through Host–Guest Chemistry |
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