Glycemic Outcomes in Adults With T1D Are Impacted More by Continuous Glucose Monitoring Than by Insulin Delivery Method: 3 Years of Follow-Up From the COMISAIR Study

Glycemic Outcomes in Adults With T1D Are Impacted More by Continuous Glucose Monitoring Than by Insulin Delivery Method: 3 Years of Follow-Up From the COMISAIR Study

This study assessed the clinical impact of four treatment strategies in adults with type 1 diabetes (T1D): real-time continuous glucose monitoring (rtCGM) with multiple daily insulin injections (rtCGM+MDI), rtCGM with continuous subcutaneous insulin infusion (rtCGM+CSII), self-monitoring of blood gl...

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Veröffentlicht in:Diabetes care 2020-01, Vol.43 (1), p.37-43
Hauptverfasser: Šoupal, Jan, Petruželková, Lenka, Grunberger, George, Hásková, Aneta, Flekač, Milan, Matoulek, Martin, Mikeš, Ondřej, Pelcl, Tomáš, Škrha, Jr, Jan, Horová, Eva, Škrha, Jan, Parkin, Christopher G, Svačina, Štěpán, Prázný, Martin
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Blood glucose
Diabetes mellitus (insulin dependent)
Glucose
Glucose monitoring
Hypoglycemia
Insulin
Monitoring
Research design
Subgroups
Therapy
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Zusammenfassung:This study assessed the clinical impact of four treatment strategies in adults with type 1 diabetes (T1D): real-time continuous glucose monitoring (rtCGM) with multiple daily insulin injections (rtCGM+MDI), rtCGM with continuous subcutaneous insulin infusion (rtCGM+CSII), self-monitoring of blood glucose with MDI (SMBG+MDI), and SMBG with CSII (SMBG+CSII). This 3-year, nonrandomized, prospective, real-world, clinical trial followed 94 participants with T1D (rtCGM+MDI, = 22; rtCGM+CSII, = 26; SMBG+MDI, = 21; SMBG+CSII, = 25). The main end points were changes in A1C, time in range (70-180 mg/dL [3.9-10 mmol/L]), time below range (
ISSN:0149-5992
1935-5548
DOI:10.2337/dc19-0888