Hybrid electrospun rapamycin-loaded small-diameter decellularized vascular grafts effectively inhibit intimal hyperplasia

Hybrid electrospun rapamycin-loaded small-diameter decellularized vascular grafts effectively inhibit intimal hyperplasia

[Display omitted] For the surgical treatment of coronary artery disease, renal artery stenosis and other peripheral vascular diseases, there is significant demand for small diameter (inner diameter

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Bibliographische Detailangaben
Veröffentlicht in:Acta biomaterialia 2019-10, Vol.97, p.321-332
Hauptverfasser: Yang, Yang, Lei, Dong, Zou, Huanxue, Huang, Shixing, Yang, Qi, Li, Sen, Qing, Feng-Ling, Ye, Xiaofeng, You, Zhengwei, Zhao, Qiang
Format: Artikel
Sprache:eng
Schlagworte:
Aorta
Autografts
Cardiovascular disease
Coronary artery
Coronary artery disease
Coronary vessels
Drug delivery
Drug delivery systems
Electrospin
Electrospinning
Grafting
Grafts
Heart diseases
Hyperplasia
Intimal hyperplasia
Macrophages
Mechanical properties
Medical treatment
Nanofibers
Polycaprolactone
Rapamycin
Renal artery
Stenosis
Stents
Tissue engineering
Transplantation
Vascular diseases
Vascular graft
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Zusammenfassung:[Display omitted] For the surgical treatment of coronary artery disease, renal artery stenosis and other peripheral vascular diseases, there is significant demand for small diameter (inner diameter
ISSN:1742-7061
1878-7568
DOI:10.1016/j.actbio.2019.06.037