Predictors and outcomes of heart failure after transcatheter aortic valve implantation using a self-expanding prosthesis

AbstractIntroduction and objectivesThe purpose of this analysis was to assess the incidence, predictors and prognostic impact of acute heart failure (AHF) after transcatheter aortic valve implantation (TAVI) using a self-expanding prosthesis. MethodsFrom November 2008 to June 2017, all consecutive p...

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Veröffentlicht in:Revista española de cardiología (English ed.) 2020-05, Vol.73 (5), p.383-392
Hauptverfasser: Cid-Menéndez, Adrián, López-Otero, Diego, González-Ferreiro, Rocío, Iglesias-Álvarez, Diego, Álvarez-Rodríguez, Leyre, Antúnez-Muiños, Pablo J, Cid-Álvarez, Belén, Sanmartin-Pena, Xoan, Trillo-Nouche, Ramiro, González-Juanatey, José R
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Sprache:eng
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Zusammenfassung:AbstractIntroduction and objectivesThe purpose of this analysis was to assess the incidence, predictors and prognostic impact of acute heart failure (AHF) after transcatheter aortic valve implantation (TAVI) using a self-expanding prosthesis. MethodsFrom November 2008 to June 2017, all consecutive patients undergoing TAVI in our center were prospectively included in our TAVI registry. The predictive effect of AHF on all-cause mortality following the TAVI procedure was analyzed using Cox regression models. ResultsA total of 399 patients underwent TAVI with a mean age of 82.4 ± 5.8 years, of which 213 (53.4%) were women. During follow-up (27.0 ± 24.1 months), 29.8% (n = 119) were admitted due to AHF, which represents a cumulative incidence function of 13.2% (95%CI, 11.1%-15.8%). At the end of follow-up, 150 patients (37.59%) had died. Those who developed AHF showed a significantly higher mortality rate (52.1% vs 31.4%; HR, 1.84; 95%; CI, 1.14-2.97; P = .012). Independent predictors of AHF after TAVI were a past history of heart failure (P = .019) and high Society of Thoracic Surgeons score (P = .004). We found that nutritional risk index and chronic obstructive pulmonary disease were strongly correlated with outcomes in the AHF group. ConclusionsTAVI was associated with a high incidence of clinical AHF. Those who developed AHF had higher mortality. Pre-TAVI AHF and high Society of Thoracic Surgeons score were the only independent predictors of AHF in our cohort. A low nutritional risk index and chronic obstructive pulmonary disease were independent markers of mortality in the AHF group.
ISSN:1885-5857
1885-5857
DOI:10.1016/j.rec.2019.06.006