PCSK9 and atherosclerosis burden in the coronary arteries of patients undergoing coronary angiography

To investigate the association between plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations, current acute coronary syndrome (ACS), coronary artery disease (CAD) presence, severity and extension and the burden of coronary calcifications in patients with suspected CAD. One hund...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical biochemistry 2019-12, Vol.74, p.12-18
Hauptverfasser:	Panahi, Yunes, Ghahrodi, Mohsen Sadeghi, Jamshir, Mohsen, Safarpour, Mohammad Amin, Bianconi, Vanessa, Pirro, Matteo, Farahani, Maryam Moshkani, Sahebkar, Amirhossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnostic imaging Acute Coronary Syndrome - pathology Age Factors Aged Angiography Atherosclerosis Atherosclerosis - diagnostic imaging Atherosclerosis - pathology Biomarkers - blood C-Reactive Protein - analysis Calcification Cardiovascular Cholesterol - blood Coronary Angiography Coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - drug therapy Coronary Artery Disease - pathology Coronary Vessels - diagnostic imaging Coronary Vessels - pathology Cross-Sectional Studies Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Male Middle Aged PCSK9 Proprotein Convertase 9 - blood Severity of Illness Index Troponin I - blood Vascular Calcification Ventricular Function, Left
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	To investigate the association between plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations, current acute coronary syndrome (ACS), coronary artery disease (CAD) presence, severity and extension and the burden of coronary calcifications in patients with suspected CAD. One hundred and one patients, with or without current ACS, were recruited for this cross-sectional study. CAD presence was defined based on either the presence or absence of at least one significant (≥50%) CAD lesion (SCAD). CAD severity was classified according to the absence of coronary lesions, the presence of non-significant (
ISSN:	0009-9120 1873-2933
DOI:	10.1016/j.clinbiochem.2019.09.001