Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure

Background: Connective tissue growth factor (CTGF) and transforming growth factor β1 (TGF-β1) are emerging biomarkers for tissue fibrosis. The aim of this study was to investigate the association between circulating CTGF, TGF-β1 levels and cardiac diastolic dysfunction in patients with diastolic hea...

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Veröffentlicht in:	Cardiology 2019-10, Vol.143 (3-4), p.77-84
Hauptverfasser:	Chi, Hongjie, Feng, Haijun, Shang, Xiangyu, Jiao, Jie, Sun, Lanlan, Jiang, Wei , Meng, Xianchen, Fan, Yifan, Lin, Xiangmin, Zhong, Jiuchang, Yang, Xinchun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Connective Tissue Growth Factor - blood Diastole Echocardiography Female Heart Failure, Diastolic - blood Heart Failure, Diastolic - diagnostic imaging Heart Failure, Diastolic - physiopathology Humans Male Middle Aged Natriuretic Peptide, Brain - blood Original Research Transforming Growth Factor beta1 - blood
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Zusammenfassung:	Background: Connective tissue growth factor (CTGF) and transforming growth factor β1 (TGF-β1) are emerging biomarkers for tissue fibrosis. The aim of this study was to investigate the association between circulating CTGF, TGF-β1 levels and cardiac diastolic dysfunction in patients with diastolic heart failure (DHF). Methods: Admitted subjects were screened for heart failure and those with left ventricular (LV) ejection fraction
ISSN:	0008-6312 1421-9751
DOI:	10.1159/000499179