Early Predictors of Enteral Autonomy in Pediatric Intestinal Failure Resulting From Short Bowel Syndrome: Development of a Disease Severity Scoring Tool

Introduction Patients with short bowel syndrome (SBS) are dependent on parenteral nutrition (PN) while their bowel attempts to compensate. Our objective was to create an SBS disease severity score to predict the probability of achieving enteral autonomy (EA). Methods A retrospective cohort study of...

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Veröffentlicht in:JPEN. Journal of parenteral and enteral nutrition 2019-11, Vol.43 (8), p.961-969
Hauptverfasser: Belza, Christina, Fitzgerald, Kevin, Silva, Nicole, Avitzur, Yaron, Wales, Paul W.
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Sprache:eng
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Zusammenfassung:Introduction Patients with short bowel syndrome (SBS) are dependent on parenteral nutrition (PN) while their bowel attempts to compensate. Our objective was to create an SBS disease severity score to predict the probability of achieving enteral autonomy (EA). Methods A retrospective cohort study of children with SBS managed by our Intestinal Rehabilitation Program was completed. Data ed included demographic, bowel anatomy, and outcome variables including conjugated bilirubin (CB) and enteral nutrition (EN) tolerated 6 months postoperatively. Univariate analysis and Cox proportional hazards (CPH) model were performed. A score was created based on weighting of coefficients. An α‐value of < 0.05 was considered significant. Results One hundred thirty‐nine patients were analyzed (61% males). Ninety‐five (68%) achieved EA. Patients possessing >50% residual small bowel (hazard ratio [HR] 2.68 [95% confidence interval {CI} 1.60‐4.49], P 
ISSN:0148-6071
1941-2444
DOI:10.1002/jpen.1691