Damage Control in the Developing Brain: Tradeoffs and Consequences

Genomic surveillance is crucial for shaping brain development. However, are these mechanisms always beneficial, and can they be manipulated to ameliorate neurodevelopmental disease? A recent paper by Shi et al. (Nat. Commun., 2019) sheds light on these questions and examines the consequences of both...

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Veröffentlicht in:	Trends in neurosciences (Regular ed.) 2019-10, Vol.42 (10), p.661-663
Hauptverfasser:	Alsina, Fernando C., Silver, Debra L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Brain genome stability Genomic Instability Humans microcephaly
Online-Zugang:	Volltext
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