Liquid biopsy in head and neck squamous cell carcinoma: Prognostic significance of circulating tumor cells and circulating tumor DNA. A systematic review

Liquid biopsy in head and neck squamous cell carcinoma: Prognostic significance of circulating tumor cells and circulating tumor DNA. A systematic review

Highlights•Liquid biopsies have great potential to detect HNSCC before clinical signs occur. •There is a lack of standardized methods for CTC and ctDNA detection in HNSCC. •There are few clinical studies on the detection of CTCs and ctDNA in HNSCC, particularly in oral cancer.

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Veröffentlicht in:Oral oncology 2019-10, Vol.97, p.7-17
Hauptverfasser: Lauritano, Dorina, Oberti, Luca, Gabrione, Federica, Lucchese, Alberta, Petruzzi, Massimo, Carinci, Francesco, Lo Muzio, Lorenzo
Format: Artikel
Sprache:eng
Schlagworte:
Hematology, Oncology, and Palliative Medicine
Otolaryngology
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Zusammenfassung:Highlights•Liquid biopsies have great potential to detect HNSCC before clinical signs occur. •There is a lack of standardized methods for CTC and ctDNA detection in HNSCC. •There are few clinical studies on the detection of CTCs and ctDNA in HNSCC, particularly in oral cancer.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2019.07.003