Y-graft modification to the Fontan procedure: Increasingly balanced flow over time

The use of Y-grafts for Fontan completion is hypothesized to offer more balanced hepatic flow distribution (HFD) and decreased energy losses. The purpose of this study was to evaluate the hemodynamic performance of Y-grafts over time using serial cardiac magnetic resonance data and to compare their...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2020-02, Vol.159 (2), p.652-661
Hauptverfasser: Trusty, Phillip M., Wei, Zhenglun, Sales, Megan, Kanter, Kirk R., Fogel, Mark A., Yoganathan, Ajit P., Slesnick, Timothy C.
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Sprache:eng
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Zusammenfassung:The use of Y-grafts for Fontan completion is hypothesized to offer more balanced hepatic flow distribution (HFD) and decreased energy losses. The purpose of this study was to evaluate the hemodynamic performance of Y-grafts over time using serial cardiac magnetic resonance data and to compare their performance with extracardiac Fontan connections. Ten Fontan patients with commercially available Y-graft connections and serial postoperative cardiac magnetic resonance data were included in this study. Patient-specific computational fluid dynamics simulations were used to estimate HFD and energy losses. Y-graft performance was compared with 3 extracardiac conduit Fontan groups (n = 10 for each) whose follow-up times straddle the Y-graft time points. Y-graft HFD became significantly more balanced over time (deviation from 50% decreased from 18% ± 14% to 8% ± 8%; P = .015). Total cavopulmonary connection resistance did not significantly change. Y-grafts at 3-year follow-up showed more balanced HFD than the extracardiac conduit groups at both the earlier and later follow-up times. Total cavopulmonary connection resistance was not significantly different between any Y-graft or extracardiac conduit group. Y-grafts showed significantly more balanced HFD over a 3-year follow-up without an increase in total cavopulmonary connection resistance, and therefore may be a valuable option for Fontan completion. Additional follow-up data at longer follow-up times are still needed to thoroughly characterize the potential advantages of Y-graft use. Improved Fontan Y-graft performance as follow-up time increases. Hepatic flow distribution (HFD) changes for a representative patient are shown. With an average follow-up time of approximately 3 years, Y-grafts (n = 10) significantly improved in terms of HFD. Nine out of 10 patients had more balanced HFD at time 2 than time 1. HFD to the left lung is indicated by percentage. LPA, Left pulmonary artery. [Display omitted]
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2019.06.063