Fast and Efficient Method to Obtain Tagitinin F by Photocyclization of Tagitinin C

There is some evidence in the literature of the photocyclization reaction of Tagitinin C (1) to Tagitinin F (2). Compound 2 has high pharmacological potential, but it is not easy to obtain, while compound 1 is easily obtained from a widespread plant, Tithonia diversifolia. Among different reaction c...

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Veröffentlicht in:Photochemistry and photobiology 2020-01, Vol.96 (1), p.14-20
Hauptverfasser: Fernandes, Victor Hugo Catricala, Viera, Natalie de Barros, Zanini, Luiza Beatriz Lima, Silva, Aline de Fátima, Salem, Paula Pio de Oliveira, Soares, Marisi Gomes, Nicácio, Karen de Jesus, Paula, Ana Claudia Chagas, Virtuoso, Luciano Sindra, Oliveira, Tiago Branquinho, Silva, Eliane de Oliveira, Dias, Danielle Ferreira, Chagas‐Paula, Daniela Aparecida
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Sprache:eng
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Zusammenfassung:There is some evidence in the literature of the photocyclization reaction of Tagitinin C (1) to Tagitinin F (2). Compound 2 has high pharmacological potential, but it is not easy to obtain, while compound 1 is easily obtained from a widespread plant, Tithonia diversifolia. Among different reaction conditions monitored, one was found that allowed the cyclization of 1 into 2 in
ISSN:0031-8655
1751-1097
DOI:10.1111/php.13148