Targeted capture and sequencing of 1245 SNPs for forensic applications

Highlights•A 1245 SNPs panel based on MIP-NGS method. •An in-house pipeline for SNP genotypes calling was designed. •Allele frequencies investigated in 210 individuals from Hubei province, China. •Suitable for SNP genotyping of degraded samples in ˜100 bp range.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Forensic science international : genetics 2019-09, Vol.42, p.227-234
Hauptverfasser:	Wu, Liangjun, Chu, Xufeng, Zheng, Jing, Xiao, Chao, Zhang, Zhe, Huang, Guiyang, Li, Dan, Zhan, Jinbang, Huang, Daixin, Hu, Ping, Xiong, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	China Chinese population Degraded DNA DNA Fingerprinting Ethnic Groups - genetics Forensic Genetics - methods Gene Frequency Genetics, Population Genotype Genotyping Techniques - methods High-Throughput Nucleotide Sequencing Humans Molecular inversion probe Molecular Probe Techniques Paternity test Pathology Polymorphism, Single Nucleotide SNP
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights•A 1245 SNPs panel based on MIP-NGS method. •An in-house pipeline for SNP genotypes calling was designed. •Allele frequencies investigated in 210 individuals from Hubei province, China. •Suitable for SNP genotyping of degraded samples in ˜100 bp range.
ISSN:	1872-4973 1878-0326
DOI:	10.1016/j.fsigen.2019.07.006