Rethinking articular cartilage regeneration based on a 250-year-old statement

Cartilage has a limited healing capacity; however, studies into the basic biological characteristics, formation and structural maintenance of the cartilage collagen network are providing explanations for the failure of current therapeutic approaches, urging us to rethink our approach to the regenera...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Rheumatology 2019-10, Vol.15 (10), p.571-572
Hauptverfasser:	Malda, Jos, Groll, Jürgen, van Weeren, P. René
Format:	Artikel
Sprache:	eng
Schlagworte:	631/61/2035 692/4023/1671/1354 692/699/1670/407 Articular cartilage Cartilage (articular) Collagen Comment Forecasts and trends Mechanical properties Medicine Medicine & Public Health Physiological aspects Regenerative medicine Rheumatology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Cartilage has a limited healing capacity; however, studies into the basic biological characteristics, formation and structural maintenance of the cartilage collagen network are providing explanations for the failure of current therapeutic approaches, urging us to rethink our approach to the regeneration of articular cartilage.
ISSN:	1759-4790 1759-4804
DOI:	10.1038/s41584-019-0278-7