Features of dipeptidyl peptidase IV (DPP‐IV) inhibitory peptides from dietary proteins

Dipeptidyl peptidase IV (DPP‐IV) is involved in incretin hormone processing and therefore plays a key role in glycemic regulation. This review summarizes the latest developments in food protein‐derived DPP‐IV inhibitory peptides. The in silico approaches currently used to develop targeted strategies for the enzymatic release of DPP‐IV inhibitory peptides from food proteins are outlined. The features within the primary sequences of potent DPP‐IV inhibitory di‐, tri‐, and larger peptides, having half maximal inhibitory activity (IC50)