Short‐term clinical outcomes of percutaneous coronary intervention of unprotected left main coronary disease in cardiogenic shock

Background Percutaneous coronary intervention (PCI) of left main (LM) disease in patients with cardiogenic shock (CS) represents a clinical challenge. Evidence on clinical outcomes according to revascularization strategies in this scenario remains scarce. The objective was to investigate the short‐term outcomes according to treatment strategies for this population. Methods We retrospectively analyzed 78 consecutive patients who underwent PCI of LM in established CS at two experienced centers. Characteristics of PCI and short‐term clinical outcomes were assessed. Results LM stenosis was considered the culprit lesion in 49 patients (62.8%). In the remaining cases, LM stenosis was treated after successful PCI of the culprit vessel because of persistent CS. The majority of patients presented complex coronary anatomy (43.6% had Syntax score > 32). Complete revascularization was performed in 34.6%; a 2‐stents technique in the LM bifurcation was used in 12.8% and intra‐aortic balloon pump (IABP) in 73.1%. In‐hospital mortality was 48.7%. At 90 days follow‐up it was 50% without differences between 1 or 2 stent LM bifurcation‐techniques (p = .319). Mortality was higher in patients with partial revascularization and residual Syntax score ≥ 15 (p