Comparative Analysis of the Antibacterial Activity and HPLC Phytochemical Screening of the Brazilian Red Propolis and the Resin of Dalbergia ecastaphyllum

The aim of this study was to investigate the antibacterial activity of red propolis and resin and their association with standard antibiotics to evaluate possible differences of activity. We also submitted red propolis and the resin to a HPLC analysis to confirm the botanical origin. The extracts we...

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Veröffentlicht in:Chemistry & biodiversity 2019-09, Vol.16 (9), p.e1900344-n/a
Hauptverfasser: Silveira Regueira‐Neto, Marcos, Relison Tintino, Saulo, Pereira da Silva, Ana Raquel, Socorro Costa, Maria, Morais Oliveira‐Tintino, Cícera Datiane, Augusti Boligon, Aline, Menezes, Irwin R. A., Queiroz Balbino, Valdir, Melo Coutinho, Henrique Douglas
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Sprache:eng
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Zusammenfassung:The aim of this study was to investigate the antibacterial activity of red propolis and resin and their association with standard antibiotics to evaluate possible differences of activity. We also submitted red propolis and the resin to a HPLC analysis to confirm the botanical origin. The extracts were tested against P. aeruginosa and S. aureus alone and in association with gentamicin and imipenem. The HPLC analysis identified seven compounds with six of them present in both substances. The lowest MIC values obtained in this study were observed against S. aureus. In general, MIC values showed to be lower for red propolis against all species tested in comparison to resin. Despite the synergistic behavior to be similar for both substances, we observed that inhibitory concentrations of drugs were lower when associated with red propolis in comparison to resin.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.201900344