How comparable are total human chorionic gonadotropin (hCGt) tumour markers assays?

Background Total human chorionic gonadotropin (hCGt) tumour marker testing is regarded as an "off label" application for most commercial methods. We compared four assays in patients with a hCGt tumour marker request. We hypothesised that regression slopes would be altered and that outliers...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2020-03, Vol.58 (3), p.438-444
Hauptverfasser:	Pretorius, Carel J., du Toit, Stephen, Wilgen, Urs, Klingberg, Sandra, Jones, Mark, Ungerer, Jacobus P.J., Tate, Jillian R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying biomarker Biomarkers, Tumor - blood Blood Chemical Analysis - standards Chorionic gonadotropin Chorionic Gonadotropin - blood Confidence intervals Decisions Female Females Gonadotropins Humans Limit of Detection Male Males Malignancy Markers oncology Outliers (statistics) Pituitary (anterior) Pregnancy Reference Standards Regression Analysis Statistical analysis Tumors tumour marker
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