Corrective osteotomies of femur and tibia: which factors influence bone healing?

Introduction Corrective osteotomies of the lower limb are standard procedures in orthopedic surgery. Still, there is only limited research on factors affecting bone healing after osteotomies. We hypothesize that especially the location of the osteotomy, smoking status and BMI affect bone healing. Material and methods The healing process of 547 patients who underwent osteotomies of the lower limb (259 female, 288 male; average 40.6 years, range 14–77) was evaluated. To assess bone healing, participants were divided into three groups by bone healing duration ( 8 months). Differences in healing duration related to the anatomic level of the osteotomy (diaphysis vs. metaphysis), age, gender, smoking status, BMI, and modus of the osteotomy (open vs. closed wedge) were tested for significance using an ordinal regression analysis. Results A significant correlation between bone healing and the anatomical level of the osteotomy on femur and tibia and the patients’ smoking status was found. The odds of the diaphysis considering bone healing was 0.187 (95% CI, 0.08–0.44) times that of the metaphysis (Wald χ 2 (1) = 14.597, p