Conversion from Prediabetes to Diabetes in Individuals with Obesity, 5-Years Post-Band, Sleeve, and Gastric Bypass Surgeries

Background Identifying risk factors for conversion to diabetes among individuals with obesity and prediabetes is important for preventing diabetes. Purpose We assessed conversion rates to diabetes 5 years after three types of metabolic surgery and examined predictors of diabetes development. Methods We accessed data of individuals with prediabetes, defined as fasting glucose (FG) 100–125 mg/dL (5.6–6.9 mmol/L) or HbA1c 5.7–6.4% at baseline (preoperatively), who underwent metabolic surgeries in Clalit Health Services during 2002–2011. Results Of 1,756 individuals with prediabetes, 819 underwent gastric banding (GB), 845 sleeve gastrectomy (SG), and 92 Roux-en-Y gastric bypass (RYGB). Mean age was 41.6 years and 73.5% were women. Five years post-surgery, 177 (10.1%) had developed diabetes. Conversion rates by type of surgery were 14.4%, 6.3%, and 6.5% for GB, SG, and RYGB, respectively ( p