Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature

Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings su...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2019-11, Vol.95 (3), p.114856-114856, Article 114856
Hauptverfasser:	Babiker, Ahmed, Clarke, Lloyd, Doi, Yohei, Shields, Ryan K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use CRE Drug Resistance, Multiple, Bacterial - drug effects ESBL Female Fosfomycin Fosfomycin - therapeutic use Humans Male Middle Aged Retrospective Studies Treatment Outcome Urinary Tract Infections - drug therapy Urinary Tract Infections - microbiology UTI VRE Young Adult
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Zusammenfassung:	Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2019.06.008