Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

Objective To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). Animals Twenty‐five eyes (24 dogs). Methods Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and...

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Veröffentlicht in:Veterinary ophthalmology 2020-01, Vol.23 (1), p.97-112
Hauptverfasser: Graham, Kathleen L., McCowan, Christina I., Caruso, Kelly, Billson, F. Mark, Whittaker, Cameron J. G., White, Andrew
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Sprache:eng
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Zusammenfassung:Objective To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). Animals Twenty‐five eyes (24 dogs). Methods Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and ONH parameters were obtained in vivo by OCT of the unaffected eye in dogs diagnosed with unilateral primary glaucoma (predisposed; n = 12) and compared with measures of healthy control eyes (normal; n = 13). Repeatability and intrarater reliability were explored using intraclass correlation coefficients (ICC). Results Compared to normal eyes, predisposed eyes had a thinner retina in the temporal (P = 0.005), inferior quadrants (P = 0.003), and decreased inner retinal thickness (superior: P = 0.003, temporal: P = 0.001, inferior: P 
ISSN:1463-5216
1463-5224
DOI:10.1111/vop.12694