Changes in cerebral oxygen saturation during one-lung ventilation determined using spatially resolved spectroscopy and contributing factors

[...]ΔTOI could be predicted as shown below, considering the time-point as a fixed effect and the case number as a random effect. ΔTOI=−3.86+0.31∗ΔSaO2+0.20∗ΔpCO2,R2=0.75661 ΔSaO2:t=2.4p=0.02ΔpCO2:t=2.3p=0.03 In our study, TOI values significantly decreased during OLV; however, the degree of desaturation was only approximately 6% from baseline. [...]intracranial cerebral desaturation during OLV may not be as severe as previously reported. The changes in CRSO2 were related to the changes in SaO2 and pCO2. [...]suppressing the decrease in SaO2 as much as possible while simultaneously maintaining PaCO2 at slightly higher levels may be important in surgery using OLV.Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.Declaration of Competing Interest None.Acknowledgements We would like to thank Editage (https://www.editage.jp/) for English language editing.