Hijack of CRISPR defences by selfish genes holds clinical promise
Parasitic genetic elements called transposons carry CRISPR machinery that is normally used against them by bacterial cells. This paradox has now been explained, with implications for gene-therapy research. RNA-guided transposition of DNA.
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| Veröffentlicht in: | Nature (London) 2019-07, Vol.571 (7764), p.180-181 |
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| container_title | Nature (London) |
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| creator | Urnov, Fyodor D. |
| description | Parasitic genetic elements called transposons carry CRISPR machinery that is normally used against them by bacterial cells. This paradox has now been explained, with implications for gene-therapy research.
RNA-guided transposition of DNA. |
| doi_str_mv | 10.1038/d41586-019-01824-0 |
| format | Article |
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| source | MEDLINE; Nature; SpringerLink Journals - AutoHoldings |
| subjects | 631/337 631/45 631/61 Analysis Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Cas Systems DNA Evolutionary genetics Gene Editing Genetic research Molecular machines News And Views RNA |
| title | Hijack of CRISPR defences by selfish genes holds clinical promise |
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