One-bloc percutaneous large biopsy of soft-tissue tumours: feasibility study and possible indications

To report the early results of the Intact lesion excision system (LES) regarding feasibility, tolerance and efficiency in obtaining soft-tissue tumour samples under ultrasound guidance. The feasibility and tolerance of Intact LES procedures under ultrasound guidance were studied prospectively in 15 patients. The procedure was performed on an outpatient basis under local anaesthesia by a single interventional radiologist with 6 years of experience and lasted around 30 min. The feasibility of the Intact LES for soft-tissue masses was good except when lesions were hard and calcified. Tolerance was good, with median pain experienced during the procedure evaluated at 4.5/10 (SD 2.2) and median post-procedural pain at day 1 evaluated at 1.8/10 (SD 2.5). No major complications were observed; however, for vascularised lesions, one case of acute wound bleeding and two post-procedural haematomas led to delayed pain. Percutaneous biopsy of suspected soft-tissue sarcoma using the LES device under ultrasound guidance is well tolerated and feasible. After a first non-contributing core biopsy, and especially, in the case of lipomatous lesions, it is a valuable option to consider, as is surgical incision biopsy. •Preoperative biopsy is important for optimal management of soft-tissue sarcoma.•Surgical biopsy is performed if image-guided core biopsy is non-contributive.•16-18-gauge biopsy analysis is at risk of underestimation.•Intact system combines Ultrasound-guided biopsy with “surgical” large sample.•Intact biopsy for soft tissue masses can safely replace surgical biopsy.