Is Antibiotic Use a Cause of IBD Worldwide?

Is Antibiotic Use a Cause of IBD Worldwide?

Antibiotic use is a plausible cause of inflammatory bowel disease (IBD). Antibiotics are widely used worldwide, including in countries where IBD is recently emerging. Especially in very early childhood, antibiotic use can impact the developing gut microbiome, with potentially lasting effects on gut...

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Veröffentlicht in:Inflammatory bowel diseases 2020-02, Vol.26 (3), p.448-449
1. Verfasser: Bernstein, Charles N
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Anti-Bacterial Agents
Antibiotics
Case-Control Studies
Child
Humans
Inflammatory Bowel Diseases
Metronidazole
Risk Factors
United Kingdom
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Zusammenfassung:Antibiotic use is a plausible cause of inflammatory bowel disease (IBD). Antibiotics are widely used worldwide, including in countries where IBD is recently emerging. Especially in very early childhood, antibiotic use can impact the developing gut microbiome, with potentially lasting effects on gut dysbiosis that may have a role in IBD development.
ISSN:1078-0998
1536-4844
DOI:10.1093/ibd/izz138