Star-like cells spark behavioural hyperactivity in mice

A molecular dialogue between neurons and star-shaped cells called astrocytes in the striatum of the mouse brain leads to behavioural hyperactivity and inattentiveness that are reminiscent of attention-deficit hyperactivity disorder. Astrocytes alter neural circuits to make mice hyperactive.

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Veröffentlicht in:Nature (London) 2019-07, Vol.571 (7763), p.43-44
Hauptverfasser: Gao, Zhihua, Hu, Hailan
Format: Artikel
Sprache:eng
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Zusammenfassung:A molecular dialogue between neurons and star-shaped cells called astrocytes in the striatum of the mouse brain leads to behavioural hyperactivity and inattentiveness that are reminiscent of attention-deficit hyperactivity disorder. Astrocytes alter neural circuits to make mice hyperactive.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-019-01949-2