Mycobacterium chimaera Encephalitis Following Cardiac Surgery: A New Syndrome

Mycobacterium chimaera Encephalitis Following Cardiac Surgery: A New Syndrome

Abstract We report the cases of 3 patients with fatal, disseminated Mycobacterium chimaera infections following cardiac surgeries. Progressive neurocognitive decline and death were explained by active granulomatous encephalitis, with widespread involvement of other organs. This syndrome is clinicall...

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Veröffentlicht in:Clinical infectious diseases 2020-02, Vol.70 (4), p.692-695
Hauptverfasser: Lau, Darren, Cooper, Ryan, Chen, Justin, Sim, Valerie L, McCombe, Jennifer A, Tyrrell, Gregory J, Bhargava, Ravi, Adam, Benjamin, Chapman, Erin, Croxen, Matthew A, Garady, Cherif, Antonation, Kym, van Landeghem, Frank K H, Ip, Shannon, Saxinger, Lynora
Format: Artikel
Sprache:eng
Schlagworte:
Cardiac Surgical Procedures - adverse effects
Encephalitis - diagnosis
Encephalitis - etiology
Humans
Mycobacterium
Mycobacterium Infections - diagnosis
Mycobacterium Infections - etiology
Mycobacterium Infections, Nontuberculous
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Zusammenfassung:Abstract We report the cases of 3 patients with fatal, disseminated Mycobacterium chimaera infections following cardiac surgeries. Progressive neurocognitive decline and death were explained by active granulomatous encephalitis, with widespread involvement of other organs. This syndrome is clinically elusive and, thus, may have caused deaths in prior reported series.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciz497