Brexanolone injection for post-partum depression treatment – Authors' reply
[...]we are grateful for the opportunity to clarify the potential role of other concomitant positive allosteric modulators of the γ-aminobutyric-acid A (GABAA) receptor. [...]most concomitant positive allosteric inhibitors used in our study were benzodiazepines, which do not share a common mechanism...
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Veröffentlicht in: | The Lancet (British edition) 2019-08, Vol.394 (10196), p.380-380 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | [...]we are grateful for the opportunity to clarify the potential role of other concomitant positive allosteric modulators of the γ-aminobutyric-acid A (GABAA) receptor. [...]most concomitant positive allosteric inhibitors used in our study were benzodiazepines, which do not share a common mechanism of action in post-partum depression as Tang and Parekh suggest. [...]please note that consumption of ethanol was not allowed during the infusion in the inpatient supervised study setting. |
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ISSN: | 0140-6736 1474-547X |
DOI: | 10.1016/S0140-6736(19)30703-2 |