The impact of diagnostic wait time on the survival of patients with diffuse large B‐cell lymphoma: effect modification by the International Prognostic Index
Summary Despite the importance of a prompt diagnosis to improve cancer patients’ survival, little has been reported on diagnostic delay in diffuse large B‐cell lymphoma (DLBCL). A single‐centre, retrospective study was conducted to examine the association between diagnostic wait time (DWT), the inte...
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Veröffentlicht in: | British journal of haematology 2019-10, Vol.187 (2), p.195-205 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Summary
Despite the importance of a prompt diagnosis to improve cancer patients’ survival, little has been reported on diagnostic delay in diffuse large B‐cell lymphoma (DLBCL). A single‐centre, retrospective study was conducted to examine the association between diagnostic wait time (DWT), the interval from the initial hospital visit to diagnosis, and survival in patients with DLBCL. A total of 193 patients were enrolled from 2007 to 2017 in our institution. A covariate‐adjusted Cox proportional hazards model with restricted cubic spline was used to evaluate the impact of DWT on survival, with a subgroup analysis according to the International Prognostic Index (IPI). DWT was not associated with survival in the entire DLBCL population, but the impact of DWT on survival differed between IPI |
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ISSN: | 0007-1048 1365-2141 |
DOI: | 10.1111/bjh.16078 |