Peridural analgesia does not impact survival in patients after colon cancer resection: a retrospective propensity score-adjusted analysis

Purpose To assess the putative impact of peridural analgesia on oncological outcome in patients undergoing resection of stages I–IV colon cancer. Methods In a single-center study, 876 patients undergoing resection for primary colon cancer (AJCC stages I–IV) between 2001 and 2014 were analyzed. Mean follow-up of the entire cohort was 4.2 ± 3.5 years. Patients who did and did not receive peridural analgesia were compared using Cox regression and propensity score analyses. Results Overall, 208 patients (23.7%) received peridural analgesia. Patients’ characteristics were biased with regard to the use of peridural analgesia (propensity score 0.296 ± 0.129 vs. 0.219 ± 0.108, p