Natural Dicarbonyls Inhibit Peroxidase Activity of Peroxiredoxins

It was established that recombinant human peroxiredoxins (Prx1, Prx2, Prx4, and Prx6) inhibit natural dicarbonyls formed during free radical peroxidation of unsaturated lipids (malonic dialdehyde) and oxidative transformations of glucose (glyoxal and methylglyoxal). A possible role of the decrease i...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2019-03, Vol.485 (1), p.132-134
Hauptverfasser:	Lankin, V. Z., Sharapov, M. G., Goncharov, R. G., Tikhaze, A. K., Novoselov, V. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Diabetes mellitus Life Sciences Lipid peroxidation Lipids Molecular Biology Molecular modelling Peroxidase Peroxidation Pyruvaldehyde
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