A pH-sensitive near-infrared fluorescent probe with alkaline pKa for chronic wound monitoring in diabetic mice
A pH-sensitive near-infrared fluorescent probe with alkaline pKa, AlkaP-1, was developed by incorporating a benzoyl hydrazine group into a cyanine dye. The significant fluorescence changes in the alkaline regions enable the probe to monitor the alkalization process from acute wounds to chronic wound...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2019-06, Vol.55 (51), p.7374-7377 |
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| container_end_page | 7377 |
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| container_issue | 51 |
| container_start_page | 7374 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 55 |
| creator | Hengtang Mai Wang, Yu Li, Shuang Jia, Ruizhen Li, Sixian Peng, Qian Xie, Yan Hu, Xiang Wu, Song |
| description | A pH-sensitive near-infrared fluorescent probe with alkaline pKa, AlkaP-1, was developed by incorporating a benzoyl hydrazine group into a cyanine dye. The significant fluorescence changes in the alkaline regions enable the probe to monitor the alkalization process from acute wounds to chronic wounds in diabetic mice. |
| doi_str_mv | 10.1039/c9cc02289a |
| format | Article |
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The significant fluorescence changes in the alkaline regions enable the probe to monitor the alkalization process from acute wounds to chronic wounds in diabetic mice.</description><subject>Alkalizing</subject><subject>Cyanine dyes</subject><subject>Diabetes</subject><subject>Fluorescent indicators</subject><subject>Hydrazines</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Rodents</subject><subject>Selectivity</subject><subject>Toxicity</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdjz9PwzAQxS0EEqWw8AkssbAE_D_xWFVAEZVYOrBVjn2mLqkd7IR-fYJg4oZ3T7qfnt4hdE3JHSVc31ttLWGs0eYEzShXopKieTv98VJXNRfyHF2UsifTUNnMUFzgflUViCUM4QtwBJOrEH02GRz23ZgyFAtxwH1OLeBjGHbYdB-mCxFw_2KwTxnbXU4xWHxMY3T4MPkh5RDfcYjYBdPCMB0PwcIlOvOmK3D1t-do8_iwWa6q9evT83KxrnpFddUapYQnVglplQLLSCud1FIr5nwtZeugdrI1VHvwhnCjPfeW1w0lyjla8zm6_Y2dSn-OUIbtIUxfdJ2JkMayZUwIKohkekJv_qH7NOY4lfuhOGeKTPoNW7xpvA</recordid><startdate>20190620</startdate><enddate>20190620</enddate><creator>Hengtang Mai</creator><creator>Wang, Yu</creator><creator>Li, Shuang</creator><creator>Jia, Ruizhen</creator><creator>Li, Sixian</creator><creator>Peng, Qian</creator><creator>Xie, Yan</creator><creator>Hu, Xiang</creator><creator>Wu, Song</creator><general>Royal Society of Chemistry</general><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>20190620</creationdate><title>A pH-sensitive near-infrared fluorescent probe with alkaline pKa for chronic wound monitoring in diabetic mice</title><author>Hengtang Mai ; Wang, Yu ; Li, Shuang ; Jia, Ruizhen ; Li, Sixian ; Peng, Qian ; Xie, Yan ; Hu, Xiang ; Wu, Song</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p619-ba664f0c645c66ec20b5d595962df755bde7d5ba19fefa03a9f3fc378106dd173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Alkalizing</topic><topic>Cyanine dyes</topic><topic>Diabetes</topic><topic>Fluorescent indicators</topic><topic>Hydrazines</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Rodents</topic><topic>Selectivity</topic><topic>Toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hengtang Mai</creatorcontrib><creatorcontrib>Wang, Yu</creatorcontrib><creatorcontrib>Li, Shuang</creatorcontrib><creatorcontrib>Jia, Ruizhen</creatorcontrib><creatorcontrib>Li, Sixian</creatorcontrib><creatorcontrib>Peng, Qian</creatorcontrib><creatorcontrib>Xie, Yan</creatorcontrib><creatorcontrib>Hu, Xiang</creatorcontrib><creatorcontrib>Wu, Song</creatorcontrib><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hengtang Mai</au><au>Wang, Yu</au><au>Li, Shuang</au><au>Jia, Ruizhen</au><au>Li, Sixian</au><au>Peng, Qian</au><au>Xie, Yan</au><au>Hu, Xiang</au><au>Wu, Song</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A pH-sensitive near-infrared fluorescent probe with alkaline pKa for chronic wound monitoring in diabetic mice</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><date>2019-06-20</date><risdate>2019</risdate><volume>55</volume><issue>51</issue><spage>7374</spage><epage>7377</epage><pages>7374-7377</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>A pH-sensitive near-infrared fluorescent probe with alkaline pKa, AlkaP-1, was developed by incorporating a benzoyl hydrazine group into a cyanine dye. 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| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2019-06, Vol.55 (51), p.7374-7377 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2244140529 |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Alkalizing Cyanine dyes Diabetes Fluorescent indicators Hydrazines NMR Nuclear magnetic resonance Rodents Selectivity Toxicity |
| title | A pH-sensitive near-infrared fluorescent probe with alkaline pKa for chronic wound monitoring in diabetic mice |
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