Selective, Intermolecular Alkylarylation of Alkenes via Photoredox/Nickel Dual Catalysis

A regioselective, intermolecular 1,2-alkylarylation of alkenes with aryl halides and alkyl oxalates has been developed via photoredox/nickel dual catalysis. This dual-catalytic protocol involves a radical relay process, where radical addition is followed by a nickel-assisted coupling, forging two consecutive C–C bonds in a single operation. The mild and redox-neutral conditions allow for good compatibility in the scope of olefins, (hetero)­aryl halides, as well as alkyl oxalates.