The Whys and Hows of Calculating Total Cellular ATP Production Rate

Quantifying total cellular ATP production rate has become easier with recent technology and is essential to understanding energy metabolism in cells and tissues. We review fundamental concepts for determining total cellular ATP production rate from measurements of oxygen consumption and acidificatio...

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Veröffentlicht in:Trends in endocrinology and metabolism 2019-07, Vol.30 (7), p.412-416
Hauptverfasser: Handel, Megan E., Brand, Martin D., Mookerjee, Shona A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Quantifying total cellular ATP production rate has become easier with recent technology and is essential to understanding energy metabolism in cells and tissues. We review fundamental concepts for determining total cellular ATP production rate from measurements of oxygen consumption and acidification rates and discuss their application to answering biological questions.
ISSN:1043-2760
1879-3061
DOI:10.1016/j.tem.2019.04.007