Thromboelastography‐Guided Blood Component Use in Patients With Cirrhosis With Nonvariceal Bleeding: A Randomized Controlled Trial

Thromboelastography (TEG) provides a more comprehensive global coagulation assessment than routine tests (international normalized ratio [INR] and platelet [PLT] count), and its use may avoid unnecessary blood component transfusion in patients with advanced cirrhosis and significant coagulopathy who...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2020-01, Vol.71 (1), p.235-246
Hauptverfasser:	Kumar, Manoj, Ahmad, Juned, Maiwall, Rakhi, Choudhury, Ashok, Bajpai, Meenu, Mitra, Lalita G., Saluja, Vandana, Mohan Agarwal, Prashant, Bihari, Chhagan, Shasthry, Saggere Muralikrishna, Jindal, Ankur, Bhardwaj, Ankit, Kumar, Guresh, Sarin, Shiv K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bleeding Blood Coagulation Disorders - diagnosis Blood Coagulation Disorders - etiology Blood Coagulation Disorders - therapy Blood Component Transfusion Blood transfusion Cirrhosis Double-Blind Method Endoscopy Female Gastrointestinal Hemorrhage - diagnosis Gastrointestinal Hemorrhage - etiology Gastrointestinal Hemorrhage - therapy Hepatology Humans Liver cirrhosis Liver Cirrhosis - complications Male Middle Aged Mortality Thrombelastography
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Zusammenfassung:	Thromboelastography (TEG) provides a more comprehensive global coagulation assessment than routine tests (international normalized ratio [INR] and platelet [PLT] count), and its use may avoid unnecessary blood component transfusion in patients with advanced cirrhosis and significant coagulopathy who have nonvariceal upper gastrointestinal (GI) bleeding. A total of 96 patients with significant coagulopathy (defined in this study as INR >1.8 and/or PLT count
ISSN:	0270-9139 1527-3350
DOI:	10.1002/hep.30794