Ten years of TRALI mitigation: measuring our progress

Ten years of TRALI mitigation: measuring our progress

BACKGROUND Transfusion‐related acute lung injury (TRALI) is a leading cause of transfusion‐associated mortality for which multiple mitigation strategies have been implemented over the past decade. However, product‐specific TRALI rates have not been reported longitudinally and may help refine additio...

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Veröffentlicht in:Transfusion (Philadelphia, Pa.) Pa.), 2019-08, Vol.59 (8), p.2567-2574
Hauptverfasser: Vossoughi, Sarah, Gorlin, Jed, Kessler, Debra A., Hillyer, Christopher D., Van Buren, Nancy L., Jimenez, Alexandra, Shaz, Beth H.
Format: Artikel
Sprache:eng
Schlagworte:
Blood Transfusion
Buffy coat
Databases, Factual
Female
Humans
Incidence
Lungs
Male
Platelets
Retrospective Studies
Risk Factors
Transfusion
Transfusion-Related Acute Lung Injury - blood
Transfusion-Related Acute Lung Injury - epidemiology
Transfusion-Related Acute Lung Injury - prevention & control
United States - epidemiology
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Zusammenfassung:BACKGROUND Transfusion‐related acute lung injury (TRALI) is a leading cause of transfusion‐associated mortality for which multiple mitigation strategies have been implemented over the past decade. However, product‐specific TRALI rates have not been reported longitudinally and may help refine additional mitigation strategies. STUDY DESIGN AND METHODS This retrospective multicenter study included analysis of TRALI rates from 2007 through 2017. Numerators included definite or probable TRALI reports from five blood centers serving nine states in the United States. Denominators were components distributed from participating centers. Rates were calculated as per 100,000 components distributed (p 
ISSN:0041-1132
1537-2995
DOI:10.1111/trf.15387