Interferon‐Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non‐human primates
We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non‐human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon‐gamma release. Initial evaluation using blood samples from Rhesus macaques experime...
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| Veröffentlicht in: | Journal of medical primatology 2019-08, Vol.48 (4), p.260-263 |
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| container_end_page | 263 |
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| container_issue | 4 |
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| container_title | Journal of medical primatology |
| container_volume | 48 |
| creator | Yee, JoAnn L. Prongay, Kamm Miles, Brodie Smedley, Jeremy Hansen, Scott G. Axthelm, Michael K. Ardeshir, Amir Van Rompay, Koen K. A. Timmel, Gregory Roberts, Jeffrey A. |
| description | We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non‐human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon‐gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals. |
| doi_str_mv | 10.1111/jmp.12420 |
| format | Article |
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A.</creatorcontrib><creatorcontrib>Timmel, Gregory</creatorcontrib><creatorcontrib>Roberts, Jeffrey A.</creatorcontrib><title>Interferon‐Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non‐human primates</title><title>Journal of medical primatology</title><addtitle>J Med Primatol</addtitle><description>We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non‐human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon‐gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.</description><subject>Animals</subject><subject>cell‐mediated immune response (CMI)</subject><subject>Enzyme-Linked Immunosorbent Assay - methods</subject><subject>Enzyme-Linked Immunosorbent Assay - veterinary</subject><subject>Immune response</subject><subject>Interferon</subject><subject>Interferon-gamma Release Tests - methods</subject><subject>Interferon-gamma Release Tests - veterinary</subject><subject>interferon‐gamma release assay (IGRA)</subject><subject>Macaca mulatta</subject><subject>Monkey Diseases - diagnosis</subject><subject>Mycobacterium tuberculosis</subject><subject>Mycobacterium tuberculosis - isolation & purification</subject><subject>purified protein derivative—tuberculin (PPD)</subject><subject>Tuberculosis</subject><subject>Tuberculosis - diagnosis</subject><issn>0047-2565</issn><issn>1600-0684</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kb9uFDEQhy1ERC6BghdAlmig2GS8Xnt3SxRBCMoJCqhXXu9Y2dPaPvxHcB01Fc_Ik8TcHSmQsAtrpM_fzOhHyHMGF6ycy43dXrC6qeERWTEJUIHsmsdkBdC0VS2kOCVnMW4AgDd984SccgZCtrJfkZ83LmEwGLz7_ePXtbJW0YQxUeMDTXdIJ0yo0-wd9Yaud9qPSpcfc7Y05RGDzouPc6Ta2-2C3-nszJGfHV0rXS61eVEpKarcRH2RBur27e6yVY5uw2xV6fmUnBi1RHx2fM_Jl3dvP1-9r24_Xt9cvbmtNO86qPqOGRCctcqM0Bgm2o73Y2fkJEcjRT3xHhlyzfuJywmw5aU0WndCyx6N4efk1cG7Df5rLrsOdo4al0U59DkOdc1rxnndsIK-_Afd-Bxcma5QAnomGwGFen2gdPAxBjTDfqWwGxgMfwIaSkDDPqDCvjga82hxeiD_JlKAywPwbV5w93_T8GH96aC8B0tvnj4</recordid><startdate>201908</startdate><enddate>201908</enddate><creator>Yee, JoAnn L.</creator><creator>Prongay, Kamm</creator><creator>Miles, Brodie</creator><creator>Smedley, Jeremy</creator><creator>Hansen, Scott G.</creator><creator>Axthelm, Michael K.</creator><creator>Ardeshir, Amir</creator><creator>Van Rompay, Koen K. A.</creator><creator>Timmel, Gregory</creator><creator>Roberts, Jeffrey A.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5514-9836</orcidid></search><sort><creationdate>201908</creationdate><title>Interferon‐Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non‐human primates</title><author>Yee, JoAnn L. ; Prongay, Kamm ; Miles, Brodie ; Smedley, Jeremy ; Hansen, Scott G. ; Axthelm, Michael K. ; Ardeshir, Amir ; Van Rompay, Koen K. 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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals cell‐mediated immune response (CMI) Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - veterinary Immune response Interferon Interferon-gamma Release Tests - methods Interferon-gamma Release Tests - veterinary interferon‐gamma release assay (IGRA) Macaca mulatta Monkey Diseases - diagnosis Mycobacterium tuberculosis Mycobacterium tuberculosis - isolation & purification purified protein derivative—tuberculin (PPD) Tuberculosis Tuberculosis - diagnosis |
| title | Interferon‐Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non‐human primates |
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