In vivo analysis and comparison of anterior segment structures of both eyes in unilateral Fuchs’ uveitis syndrome

Purpose To compare corneal endothelial cell density (ECD), iris stromal thickness (IST), iris pigment epithelium optical density (IPE OD), and Schlemm’s canal (SC) measurements in patients having unilateral Fuchs’ uveitis syndrome (FUS). Methods This is a randomized, prospective study. Currently, diagnosed unilateral FUS and phakic cases were defined to be the inclusion criteria to the study. The specular microscope was used to measure ECD. Anterior segment images were acquired by using SD-OCT. The images were extracted and uploaded to the ImageJ program for further analysis. Two blinded investigators analyzed the IST, IPE OD, and SC area in both healthy ( N ) and affected eyes (FUS) and the comparative analysis was made by using SPSS program. Results Of twenty-one participants, 13 were female (62%). The mean age of the participants was 30 ± 9 (18–47) years. ECD was 2228 ± 365 and 2513 ± 209 cells/mm 2 in the FUS and N , respectively ( p