Doripenem dosing regimens in Asian critically ill patients with continuous renal replacement therapy

Doripenem dosing regimens in Asian critically ill patients with continuous renal replacement therapy

•Drug dosing regimens based on Asian pharmacokinetic study is limited.•The optimal doripenem dosing regimen in Asian patients receiving CRRT was a 500 mg every 8 h for P. aeruginosa infection.•Effluent rates of CRRT and body weight play major contributions for doripenem dosing regimens.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of critical care 2019-08, Vol.52, p.233-236
Hauptverfasser: Chaijamorn, Weerachai, Puchsaka, Punyawee, Pattharachayakul, Sutthiporn, Charoensareerat, Taniya, Srisawat, Nattachai, Boonpeng, Apinya, Pummangura, Chalermsri
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Antimicrobial agents
Drug dosages
Effluents
Epidemiology
Hemodialysis
Intensive care
Kidney diseases
Medical prognosis
Mortality
Patients
Population
Renal replacement therapy
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:•Drug dosing regimens based on Asian pharmacokinetic study is limited.•The optimal doripenem dosing regimen in Asian patients receiving CRRT was a 500 mg every 8 h for P. aeruginosa infection.•Effluent rates of CRRT and body weight play major contributions for doripenem dosing regimens.
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2019.04.030