Expression analysis of a panel of long non-coding RNAs (lncRNAs) revealed their potential as diagnostic biomarkers in bladder cancer

Expression analysis of a panel of long non-coding RNAs (lncRNAs) revealed their potential as diagnostic biomarkers in bladder cancer

Long non-coding RNAs (lncRNAs) have fundamental roles in cell migration, proliferation, invasion and metastasis. In the current study, we evaluated expression of a panel of lncRNAs in bladder cancer tissues, adjacent non-cancerous tissues (ANCTs) and normal bladder tissues to evaluate their diagnost...

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Veröffentlicht in:Genomics (San Diego, Calif.) Calif.), 2020-01, Vol.112 (1), p.677-682
Hauptverfasser: Abdolmaleki, Feraydoon, Ghafoui-Fard, Soudeh, Taheri, Mohammad, Mordadi, Alireza, Afsharpad, Mandana, Varmazyar, Sajad, Nazparvar, Bashir, Oskooei, Vahid Kholghi, Omrani, Mir Davood
Format: Artikel
Sprache:eng
Schlagworte:
Bladder cancer
DLEU2
DSCAM-AS1
FAS-AS1
GHET1
HOTAIR
HOTAIRM1
lncRNA
NEAT1
THRIL
TUG1
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Zusammenfassung:Long non-coding RNAs (lncRNAs) have fundamental roles in cell migration, proliferation, invasion and metastasis. In the current study, we evaluated expression of a panel of lncRNAs in bladder cancer tissues, adjacent non-cancerous tissues (ANCTs) and normal bladder tissues to evaluate their diagnostic power. PV1 was down-regulated in tumor tissues compared with both ANCTs and normal controls (Expression ratios of 0.48 and 0.14; P values of 0.4 and
ISSN:0888-7543
1089-8646
DOI:10.1016/j.ygeno.2019.04.020