Invasive mold disease of the central nervous system in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation: Analysis of 29 contemporary patients

Invasive mold disease of the central nervous system in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation: Analysis of 29 contemporary patients

Background Invasive mold disease (IMD) is a severe infectious complication in immunocompromised patients. The outcome of central nervous system (CNS) IMD is poor, but contemporary data, in particular in the pediatric setting, are lacking. Procedure For this retrospective multicenter analysis, pediat...

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Veröffentlicht in:Pediatric blood & cancer 2019-08, Vol.66 (8), p.e27806-n/a
Hauptverfasser: Lauten, Melchior, Attarbaschi, Andishe, Cario, Gunnar, Döring, Michaela, Moser, Olga, Mücke, Urs, Poyer, Fiona, Rieken, Sarah, Temme, Christian, Voigt, Sebastian, Lehrnbecher, Thomas, Groll, Andreas H.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adolescents
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Autopsies
Autopsy
Central nervous system
Central Nervous System Diseases - pathology
Central Nervous System Diseases - therapy
Cerebrospinal fluid
Chemotherapy
Child
Child, Preschool
Children
Combined Modality Therapy
Female
Follow-Up Studies
fungal infection
Germany - epidemiology
Hematologic Neoplasms - pathology
Hematologic Neoplasms - therapy
Hematology
Hematopoietic Stem Cell Transplantation - adverse effects
Hematopoietic stem cells
Humans
Immunocompromised hosts
Incidence
Infant
Invasive Fungal Infections - epidemiology
Invasive Fungal Infections - etiology
Invasive Fungal Infections - microbiology
Invasiveness
late sequelae
Male
Mold
Nervous system
Neuroimaging
Neurological complications
Oncology
Pediatrics
Prognosis
Retrospective Studies
Stem cell transplantation
Survival Rate
Transplantation
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Zusammenfassung:Background Invasive mold disease (IMD) is a severe infectious complication in immunocompromised patients. The outcome of central nervous system (CNS) IMD is poor, but contemporary data, in particular in the pediatric setting, are lacking. Procedure For this retrospective multicenter analysis, pediatric patients 
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.27806