Mediastinal Mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation

Mediastinal Mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation

Summary Mediastinal mucormycosis is an uncommon but lethal infection associated with an 83% mortality. We describe a case of fatal Rhizopus microsporus mediastinitis despite three exploratory mediastinal surgeries and complementary systemic and mediastinal irrigation with liposomal amphotericin B. W...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mycoses 2019-09, Vol.62 (9), p.739-745
Hauptverfasser: Cooper, Joseph D., Gotoff, Robert A., Foltzer, Michael A., Carter, Russell A., Walsh, Thomas J.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Amphotericin B
Amphotericin B - therapeutic use
Antifungal Agents - therapeutic use
Case reports
Fatal Outcome
Female
Humans
Lavage
liposomal amphotericin B irrigation
Mediastinal Diseases - diagnosis
Mediastinal Diseases - drug therapy
Mediastinal Diseases - microbiology
Mediastinal Diseases - surgery
mediastinal mucormycosis
Mediastinitis
Mucormycosis
Mucormycosis - diagnosis
Mucormycosis - drug therapy
Rhizopus - drug effects
Therapeutic Irrigation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Summary Mediastinal mucormycosis is an uncommon but lethal infection associated with an 83% mortality. We describe a case of fatal Rhizopus microsporus mediastinitis despite three exploratory mediastinal surgeries and complementary systemic and mediastinal irrigation with liposomal amphotericin B. We further review the literature on surgical and antifungal management of mediastinal mucormycosis.
ISSN:0933-7407
1439-0507
DOI:10.1111/myc.12922