Performance of target-controlled infusion of propofol in plasma versus effect-site control during induction in elderly patients: A Letter To The Editor

[Display omitted] •There is a debate whether TCI of propofol in effect-site control is superior to plasma control and which model to choose.•Most assumptions on performance of either modality are based on simulated comparisons and prospective clinical comparisons are sparse.•TCI in plasma control us...

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Veröffentlicht in:	Journal of clinical anesthesia 2019-12, Vol.58, p.9-11
Hauptverfasser:	Schraag, Stefan, Petscher, Matthias, Wachter, Ulrich, Kreuer, Sascha, Kenny, Gavin, Wagner, Florian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia Anesthetics, Intravenous - administration & dosage Anesthetics, Intravenous - blood Consciousness Humans Models, Biological Propofol - administration & dosage Propofol - blood Prospective Studies
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Zusammenfassung:	[Display omitted] •There is a debate whether TCI of propofol in effect-site control is superior to plasma control and which model to choose.•Most assumptions on performance of either modality are based on simulated comparisons and prospective clinical comparisons are sparse.•TCI in plasma control using the Marsh model allows a faster induction as compared with effect-site control.•We could not identify a clinical advantage of using effect-site TCI with the Schnider model.
ISSN:	0952-8180 1873-4529
DOI:	10.1016/j.jclinane.2019.04.013